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MHC Class I Tetramer Reagents

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MHC Class I Tetramer Reagents Antigen Specific T Cell Tracking The development of MHC peptide tetramers has allowed direct insights into the frequency, distribution and dynamics of the cellular immune response. Monitoring T cell responses is now possible in a range of infectious diseases such as Influenza, Hepatitis B (HBV) and C (HCV), HIV, Cytomegalo (CMV) and Epstein Barr Virus (EBV) as well as in cancer research, transplantation immunology and vaccine development. The multivalent nature of the tetramer increases the avidity and results in stable binding of tetramers to the corresponding antigen-specific T cells. CD8+ T cells recognize virally infected cells or tumor cells and use cytotoxic molecules to kill the target cell. T cells that are stimulated by antigen are developmentally programmed to divide at least 7 - 10 times and to differentiate into effector cytotoxic T lymphocytes and long lived, functional memory CD8+ T cells. This polyclonal expansion of antigen-specific T cells can be monitored with tetramers. The number of tetramer-positive and CD8-positive T cells is determined by flow cytometry. Figure to the right: MHC-peptide molecules elicit cytolytic T cell responses and stimulate the expansion of antigen-specific T cells. Class I Tetramers provide a powerfull and general tool for the study of antigen-specific T cells.


Products

ITEM  CLONE  FORMAT  SOURCE  SIZE  CATALOG NO. 
Tetramer Matching Peptides, CINGVCWTV, 5-10 mg   Unconjugated Virus 5~10 mg PEP-0302
Tetramer Matching Peptides, CLGGLLTMV, 5-10 mg   Unconjugated Virus 5~10 mg PEP-0402
Tetramer Matching Peptides, DLMGYIPAV, 5-10 mg   Unconjugated Virus 5~10 mg PEP-0301
Tetramer Matching Peptides, ELAGIGILTV, 5-10 mg   Unconjugated Human 5~10 mg PEP-1003
Tetramer Matching Peptides, FLLSLGIHL, 5-10 mg   Unconjugated Virus 5~10 mg PEP-0205
Tetramer Matching Peptides, FLLTRILTI, 5-10 mg   Unconjugated Virus 5~10 mg PEP-0202
Tetramer Matching Peptides, FLPSDFFPSV, 5-10 mg   Unconjugated Virus 5~10 mg PEP-0201
Tetramer Matching Peptides, GILGFVFTL, 5-10 mg   Unconjugated Virus 5~10 mg PEP-0601
Tetramer Matching Peptides, GLCTLVAML, 5-10 mg   Unconjugated Virus 5~10 mg PEP-0401
Tetramer Matching Peptides, GLPVEYLQV, 5-10 mg   Unconjugated Bacteria 5~10 mg PEP-0902
Tetramer Matching Peptides, GLSPTVWLSV, 5-10 mg   Unconjugated Virus 5~10 mg PEP-0203
Tetramer Matching Peptides, ILAKFLHWL, 5-10 mg   Unconjugated Human 5~10 mg PEP-1009
Tetramer Matching Peptides, ILKEPVHGV, 5-10 mg   Unconjugated Virus 5~10 mg PEP-0101
Tetramer Matching Peptides, IMDQVPFSV, 5-10 mg   Unconjugated Human 5~10 mg PEP-1002
Tetramer Matching Peptides, ITDQVPFSV, 5-10 mg   Unconjugated Human 5~10 mg PEP-1001
ITEM  CLONE  FORMAT  SOURCE  SIZE  CATALOG NO. 
Tetramer Matching Peptides, KIFGSLLAFL, 5-10 mg   Unconjugated Human 5~10 mg PEP-1004
Tetramer Matching Peptides, KLIANNTRV, 5-10 mg   Unconjugated Bacteria 5~10 mg PEP-0901
Tetramer Matching Peptides, KLTPLCVTL, 5-10 mg   Unconjugated Virus 5~10 mg PEP-0104
Tetramer Matching Peptides, KLVALGINAV, 5-10 mg   Unconjugated Virus 5~10 mg PEP-0303
Tetramer Matching Peptides, LLFGYPVYV, 5-10 mg   Unconjugated Virus 5~10 mg PEP-0801
Tetramer Matching Peptides, NLVPMVATV, 5-10 mg   Unconjugated Virus 5~10 mg PEP-0501
Tetramer Matching Peptides, NMFTPYIGV, 5-10 mg   Unconjugated Bacteria 5~10 mg PEP-0904
Tetramer Matching Peptides, RLLQETELV, 5-10 mg   Unconjugated Human 5~10 mg PEP-1005
Tetramer Matching Peptides, RLNMFTPYI, 5-10 mg   Unconjugated Bacteria 5~10 mg PEP-0903
Tetramer Matching Peptides, RMFPNAPYL, 5-10 mg   Unconjugated Human 5~10 mg PEP-1008
Tetramer Matching Peptides, SIINFEKL, 5-10 mg   Unconjugated Chicken 5~10 mg PEP-1101
Tetramer Matching Peptides, SLYNTVATL, 5-10 mg   Unconjugated Virus 5~10 mg PEP-0102
Tetramer Matching Peptides, TLNAWVKVV, 5-10 mg   Unconjugated Virus 5~10 mg PEP-0103
Tetramer Matching Peptides, VLQELNVTV, 5-10 mg   Unconjugated Human 5~10 mg PEP-1006
Tetramer Matching Peptides, WLSLLVPFV, 5-10 mg   Unconjugated Virus 5~10 mg PEP-0204
ITEM  CLONE  FORMAT  SOURCE  SIZE  CATALOG NO. 
Tetramer Matching Peptides, YLNKIQNSL, 5-10 mg   Unconjugated Bacteria 5~10 mg PEP-0905
Tetramer Matching Peptides, YMDGTMSQV, 5-10 mg   Unconjugated Human 5~10 mg PEP-1007
Tetramer Matching Peptides, YMLDLQPETT, 5-10 mg   Unconjugated Virus 5~10 mg PEP-0701
Tetramer, Chlamydia, APC-labeled, NMFTPYIGV, 50 tests   APC Bacteria 50 tests T-0904APC
Tetramer, Chlamydia, APC-labeled, RLNMFTPYI, 50 tests   APC Bacteria 50 tests T-0903APC
Tetramer, Chlamydia, PE-labeled, NMFTPYIGV, 50 tests   PE Bacteria 50 tests T-0904PE
Tetramer, Chlamydia, PE-labeled, RLNMFTPYI, 50 tests   PE Bacteria 50 tests T-0903PE
Tetramer, CMV pp65, APC-labeled, NLVPMVATV, 50 tests   APC Virus 50 tests T-0501APC
Tetramer, CMV pp65, PE-labeled, NLVPMVATV, 50 tests   PE Virus 50 tests T-0501PE
Tetramer, EBV BMLF-1, APC-labeled, GLCTLVAML, 50 tests   APC Virus 50 tests T-0401APC
Tetramer, EBV BMLF-1, PE-labeled, GLCTLVAML, 50 tests   PE Virus 50 tests T-0401PE
Tetramer, EBV LMP2, APC-labeled, CLGGLLTMV, 50 tests   APC Virus 50 tests T-0402APC
Tetramer, EBV LMP2, PE-labeled, CLGGLLTMV, 50 tests   PE Virus 50 tests T-0402PE
Tetramer, Gp 100, APC-labeled, IMDQVPFSV, 50 tests   APC Human 50 tests T-1002APC
Tetramer, Gp 100, APC-labeled, ITDQVPFSV, 50 tests   APC Human 50 tests T-1001APC
ITEM  CLONE  FORMAT  SOURCE  SIZE  CATALOG NO. 
Tetramer, Gp 100, PE-labeled, IMDQVPFSV, 50 tests   PE Human 50 tests T-1002PE
Tetramer, Gp 100, PE-labeled, ITDQVPFSV, 50 tests   PE Human 50 tests T-1001PE
Tetramer, HBV core, APC-labeled, FLPSDFFPSV, 50 tests   APC Virus 50 tests T-0201APC
Tetramer, HBV core, PE-labeled, FLPSDFFPSV, 50 tests   PE Virus 50 tests T-0201PE
Tetramer, HBV pol, APC-labeled, FLLSLGIHL, 50 tests   APC Virus 50 tests T-0205APC
Tetramer, HBV pol, PE-labeled, FLLSLGIHL, 50 tests   PE Virus 50 tests T-0205PE
Tetramer, HBV sAg, APC-labeled, FLLTRILTI, 50 tests   APC Virus 50 tests T-0202APC
Tetramer, HBV sAg, APC-labeled, GLSPTVWLSV, 50 tests   APC Virus 50 tests T-0203APC
Tetramer, HBV sAg, APC-labeled, WLSLLVPFV, 50 tests   APC Virus 50 tests T-0204APC
Tetramer, HBV sAg, PE-labeled, FLLTRILTI, 50 tests   PE Virus 50 tests T-0202PE
Tetramer, HBV sAg, PE-labeled, GLSPTVWLSV, 50 tests   PE Virus 50 tests T-0203PE
Tetramer, HBV sAg, PE-labeled, WLSLLVPFV, 50 tests   PE Virus 50 tests T-0204PE
Tetramer, HCV core, APC-labeled, DLMGYIPAV, 50 tests   APC Virus 50 tests T-0301APC
Tetramer, HCV core, PE-labeled, DLMGYIPAV, 50 tests   PE Virus 50 tests T-0301PE
Tetramer, HCV NS3, APC-labeled, CINGVCWTV, 50 tests   APC Virus 50 tests T-0302APC
ITEM  CLONE  FORMAT  SOURCE  SIZE  CATALOG NO. 
Tetramer, HCV NS3, APC-labeled, KLVALGINAV, 50 tests   APC Virus 50 tests T-0303APC
Tetramer, HCV NS3, PE-labeled, CINGVCWTV, 50 tests   PE Virus 50 tests T-0302PE
Tetramer, HCV NS3, PE-labeled, KLVALGINAV, 50 tests   PE Virus 50 tests T-0303PE
Tetramer, HER-2/neu, APC-labeled, KIFGSLLAFL, 50 tests   APC Human 50 tests T-1004APC
Tetramer, HER-2/neu, APC-labeled, RLLQETELV, 50 tests   APC Human 50 tests T-1005APC
Tetramer, HER-2/neu, PE-labeled, KIFGSLLAFL, 50 tests   PE Human 50 tests T-1004PE
Tetramer, HER-2/neu, PE-labeled, RLLQETELV, 50 tests   PE Human 50 tests T-1005PE
Tetramer, HIV enf, APC-labeled, KLTPLCVTL, 50 tests   APC Virus 50 tests T-0104APC
Tetramer, HIV enf, PE-labeled, KLTPLCVTL, 50 tests   PE Virus 50 tests T-0104PE
Tetramer, HIV gag, APC-labeled, SLYNTVATL, 50 tests   APC Virus 50 tests T-0102APC
Tetramer, HIV gag, APC-labeled, TLNAWVKVV, 50 tests   APC Virus 50 tests T-0103APC
Tetramer, HIV gag, PE-labeled, SLYNTVATL, 50 tests   PE Virus 50 tests T-0102PE
Tetramer, HIV gag, PE-labeled, TLNAWVKVV, 50 tests   PE Virus 50 tests T-0103PE
Tetramer, HIV-RT, APC-labeled, ILKEPVHGV, 50 tests   APC Virus 50 tests T-0101APC
Tetramer, HIV-RT, PE-labeled, ILKEPVHGV, 50 tests   PE Virus 50 tests T-0101PE
ITEM  CLONE  FORMAT  SOURCE  SIZE  CATALOG NO. 
Tetramer, HPV E7, APC-labeled, YMLDLQPETT, 50 tests   APC Virus 50 tests T-0701APC
Tetramer, HPV E7, PE-labeled, YMLDLQPETT, 50 tests   PE Virus 50 tests T-0701PE
Tetramer, HTLV-1 tax, APC-labeled, LLFGYPVYV, 50 tests   APC Virus 50 tests T-0801APC
Tetramer, HTLV-1 tax, PE-labeled, LLFGYPVYV, 50 tests   PE Virus 50 tests T-0801PE
Tetramer, Influenza M1, APC-labeled, GILGFVFTL, 50 tests   APC Virus 50 tests T-0601APC
Tetramer, Influenza M1, PE-labeled, GILGFVFTL, 50 tests   PE Virus 50 tests T-0601PE
Tetramer, M. bovis 85A, APC-labeled, GLPVEYLQV, 50 tests   APC Bacteria 50 tests T-0902APC
Tetramer, M. bovis 85A, APC-labeled, KLIANNTRV, 50 tests   APC Bacteria 50 tests T-0901APC
Tetramer, M. bovis 85A, PE-labeled, GLPVEYLQV, 50 tests   PE Bacteria 50 tests T-0902PE
Tetramer, M. bovis 85A, PE-labeled, KLIANNTRV, 50 tests   PE Bacteria 50 tests T-0901PE
Tetramer, MART-1, APC-labeled, ELAGIGILTV, 50 tests   APC Human 50 tests T-1003APC
Tetramer, MART-1, PE-labeled, ELAGIGILTV, 50 tests   PE Human 50 tests T-1003PE
Tetramer, Ovalbumin, APC-labeled, SIINFEKL, 50 tests   APC Chicken 50 tests T-1101APC
Tetramer, Ovalbumin, PE-labeled, SIINFEKL, 50 tests   PE Chicken 50 tests T-1101PE
Tetramer, P. falciparum, APC-labeled, YLNKIQNSL, 50 tests   APC Bacteria 50 tests T-0905APC
ITEM  CLONE  FORMAT  SOURCE  SIZE  CATALOG NO. 
Tetramer, P. falciparum, PE-labeled, YLNKIQNSL, 50 tests   PE Bacteria 50 tests T-0905PE
Tetramer, Proteinase 3, APC-labeled, VLQELNVTV, 50 tests   APC Human 50 tests T-1006APC
Tetramer, Proteinase 3, PE-labeled, VLQELNVTV, 50 tests   PE Human 50 tests T-1006PE
Tetramer, Telomerase, APC-labeled, ILAKFLHWL, 50 tests   APC Human 50 tests T-1009APC
Tetramer, Telomerase, PE-labeled, ILAKFLHWL, 50 tests   PE Human 50 tests T-1009PE
Tetramer, Tyrosinase, APC-labeled, YMDGTMSQV, 50 tests   APC Human 50 tests T-1007APC
Tetramer, Tyrosinase, PE-labeled, YMDGTMSQV, 50 tests   PE Human 50 tests T-1007PE
Tetramer, WT-1, APC-labeled, RMFPNAPYL, 50 tests   APC Human 50 tests T-1008APC
Tetramer, WT-1, PE-labeled, RMFPNAPYL, 50 tests   PE Human 50 tests T-1008PE

ITEM  CLONE  FORMAT  SOURCE  SIZE  CATALOG NO. 
Biotinylated MHC-Peptide Monomers, CINGVCWTV, 100 µg   Biotin Virus 100 ug M-0302
Biotinylated MHC-Peptide Monomers, CLGGLLTMV, 100 µg   Biotin Virus 100 ug M-0402
Biotinylated MHC-Peptide Monomers, DLMGYIPAV, 100 µg   Biotin Virus 100 ug M-0301
Biotinylated MHC-Peptide Monomers, ELAGIGILTV, 100 µg   Biotin Human 100 ug M-1003
Biotinylated MHC-Peptide Monomers, FLLSLGIHL, 100 µg   Biotin Virus 100 ug M-0205
Biotinylated MHC-Peptide Monomers, FLLTRILTI, 100 µg   Biotin Virus 100 ug M-0202
Biotinylated MHC-Peptide Monomers, FLPSDFFPSV, 100 µg   Biotin Virus 100 ug M-0201
Biotinylated MHC-Peptide Monomers, GILGFVFTL, 100 µg   Biotin Virus 100 ug M-0601
Biotinylated MHC-Peptide Monomers, GLCTLVAML, 100 µg   Biotin Virus 100 ug M-0401
Biotinylated MHC-Peptide Monomers, GLPVEYLQV, 100 µg   Biotin Bacteria 100 ug M-0902
Biotinylated MHC-Peptide Monomers, GLSPTVWLSV, 100 µg   Biotin Virus 100 ug M-0203
Biotinylated MHC-Peptide Monomers, ILAKFLHWL, 100 µg   Biotin Human 100 ug M-1009
Biotinylated MHC-Peptide Monomers, ILKEPVHGV, 100 µg   Biotin Virus 100 ug M-0101
Biotinylated MHC-Peptide Monomers, IMDQVPFSV, 100 µg   Biotin Human 100 ug M-1002
Biotinylated MHC-Peptide Monomers, ITDQVPFSV, 100 µg   Biotin Human 100 ug M-1001
ITEM  CLONE  FORMAT  SOURCE  SIZE  CATALOG NO. 
Biotinylated MHC-Peptide Monomers, KIFGSLLAFL, 100 µg   Biotin Human 100 ug M-1004
Biotinylated MHC-Peptide Monomers, KLIANNTRV, 100 µg   Biotin Bacteria 100 ug M-0901
Biotinylated MHC-Peptide Monomers, KLTPLCVTL, 100 µg   Biotin Virus 100 ug M-0104
Biotinylated MHC-Peptide Monomers, KLVALGINAV, 100 µg   Biotin Virus 100 ug M-0303
Biotinylated MHC-Peptide Monomers, LLFGYPVYV, 100 µg   Biotin Virus 100 ug M-0801
Biotinylated MHC-Peptide Monomers, NLVPMVATV, 100 µg   Biotin Virus 100 ug M-0501
Biotinylated MHC-Peptide Monomers, NMFTPYIGV, 100 µg   Biotin Bacteria 100 ug M-0904
Biotinylated MHC-Peptide Monomers, RLLQETELV, 100 µg   Biotin Human 100 ug M-1005
Biotinylated MHC-Peptide Monomers, RLNMFTPYI, 100 µg   Biotin Bacteria 100 ug M-0903
Biotinylated MHC-Peptide Monomers, RMFPNAPYL, 100 µg   Biotin Human 100 ug M-1008
Biotinylated MHC-Peptide Monomers, SIINFEKL, 100 µg   Biotin Chicken 100 ug M-1101
Biotinylated MHC-Peptide Monomers, SLYNTVATL, 100 µg   Biotin Virus 100 ug M-0102
Biotinylated MHC-Peptide Monomers, TLNAWVKVV, 100 µg   Biotin Virus 100 ug M-0103
Biotinylated MHC-Peptide Monomers, VLQELNVTV, 100 µg   Biotin Human 100 ug M-1006
Biotinylated MHC-Peptide Monomers, WLSLLVPFV, 100 µg   Biotin Virus 100 ug M-0204
ITEM  CLONE  FORMAT  SOURCE  SIZE  CATALOG NO. 
Biotinylated MHC-Peptide Monomers, YLNKIQNSL, 100 µg   Biotin Bacteria 100 ug M-0905
Biotinylated MHC-Peptide Monomers, YMDGTMSQV, 100 µg   Biotin Human 100 ug M-1007
Biotinylated MHC-Peptide Monomers, YMLDLQPETT, 100 µg   Biotin Virus 100 ug M-0701


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San Diego, CA 92121 USA

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Toll free: 866.672.4436
Fax: 858.200.2038
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