All Pathways
	Observe how genes interact in dynamic graphical models. Our online maps depict molecular relationships from areas of active research. In an "open source" approach, this community-fed forum constantly integrates emerging proteomic information from the scientific community. It also catalogs and summarizes important resources providing information for over 120,000 genes from multiple species. Find both classical pathways as well as current suggestions for new pathways.

A Acetylation and Deacetylation of RelA in The Nucleus Actions of Nitric Oxide in the Heart Activation of cAMP-dependent protein kinase, PKA Activation of Csk by cAMP-dependent Protein Kinase Inhibits Signaling through the T Cell Receptor Activation of PKC through G protein coupled receptor Activation of Src by Protein-tyrosine phosphatase alpha Acute Myocardial Infarction Adhesion Molecules on Lymphocyte Ahr Signal Transduction Pathway AKAP95 role in mitosis and chromosome dynamics AKT Signaling Pathway ALK in cardiac myocytes Alpha-synuclein and Parkin-mediated proteolysis in Parkinson's disease Alternative Complement Pathway Angiotensin II mediated activation of JNK Pathway via Pyk2 dependent signaling Angiotensin-converting enzyme 2 regulates heart function Anthrax Toxin Mechanism of Action Antigen Dependent B Cell Activation Apoptotic DNA fragmentation and tissue homeostasis Apoptotic Signaling in Response to DNA Damage Aspirin Blocks Signaling Pathway Involved in Platelet Activation ATM Signaling Pathway Attenuation of GPCR Signaling B B Cell Receptor Complex B Lymphocyte Cell Surface Molecules Basic mechanism of action of PPARa, PPARb(d) and PPARg and effects on gene expression Basic Mechanisms of SUMOylation BCR Signaling Pathway Beta-Oxidation of Fatty Acids Bioactive Peptide Induced Signaling Pathway Biosynthesis of Arginine in Bacteria Biosynthesis of Chorismate in Bacteria and Plants Biosynthesis of Cysteine from serine in bacteria and plants Biosynthesis of Cysteine in mammals Biosynthesis of Glycine and Serine Biosynthesis of isoleucine Biosynthesis of leucine Biosynthesis of Lysine Biosynthesis of neurotransmitters Biosynthesis of phenylalanine and tyrosine in bacteria and plants Biosynthesis of Proline in Bacteria Biosynthesis of spermidine and spermine Biosynthesis of sphingolipids Biosynthesis of threonine and methionine Biosynthesis of Tryptophan in Bacteria and Plants Biosynthesis of valine Blockade of Neurotransmitter Relase by Botulinum Toxin Bone Remodelling Bystander B Cell Activation C Ca++/ Calmodulin-dependent Protein Kinase Activation Cadmium induces DNA synthesis and proliferation in macrophages Calcium Signaling by HBx of Hepatitis B virus Cardiac Protection Against ROS CARM1 and Regulation of the Estrogen Receptor Caspase Cascade in Apoptosis Catabolic pathway for asparagine and asparate Catabolic pathways for alanine, glycine, serine, cysteine, tryptophan, and threonine Catabolic Pathways for Arginine , Histidine, Glutamate, Glutamine, and Proline Catabolic Pathways for Methionine, Isoleucine, Threonine and Valine CBL mediated ligand-induced downregulation of EGF receptors CCR3 signaling in Eosinophils CD40L Signaling Pathway cdc25 and chk1 Regulatory Pathway in response to DNA damage Cell Cycle: G1/S Check Point Cell Cycle: G2/M Checkpoint Cell to Cell Adhesion Signaling Cells and Molecules involved in local acute inflammatory response Ceramide Signaling Pathway Chaperones modulate interferon Signaling Pathway ChREBP regulation by carbohydrates and cAMP Circadian Rhythms Classical Complement Pathway Comparison of Beta oxidation in mitochondria and peroxisomes and glyoxysomes Complement Pathway Control of skeletal myogenesis by HDAC & calcium/calmodulin-dependent kinase (CaMK) Corticosteroids and cardioprotection CTL mediated immune response against target cells CXCR4 Signaling Pathway Cyclin E Destruction Pathway Cycling of Ran in nucleocytoplasmic transport Cyclins and Cell Cycle Regulation Cytokine Network Cytokines and Inflammatory Response D D4-GDI Signaling Pathway Degradation of the RAR and RXR by the proteasome Dendritic cells in regulating TH1 and TH2 Development Deregulation of CDK5 in Alzheimers Disease Double Stranded RNA Induced Gene Expression E E2F1 Destruction Pathway Effects of calcineurin in Keratinocyte Differentiation EGF Signaling Pathway Electron Transport Reaction in Mitochondria Endocytotic role of NDK, Phosphins and Dynamin Eph Kinases and ephrins support platelet aggregation EPO Signaling Pathway Erk and PI-3 Kinase Are Necessary for Collagen Binding in Corneal Epithelia Erk1/Erk2 Mapk Signaling pathway Erythrocyte Differentiation Pathway Erythropoietin mediated neuroprotection through NF-kB Extrinsic Prothrombin Activation Pathway F FAS signaling pathway ( CD95 ) Fc Epsilon Receptor I Signaling in Mast Cells Feeder Pathways for Glycolysis Fibrinolysis Pathway fMLP induced chemokine gene expression in HMC-1 cells Formation of Ketone Bodies from acetyl-CoA FOSB gene expression and drug abuse Free Radical Induced Apoptosis Function of SLRP in Bone: An Integrated View FXR and LXR Regulation of Cholesterol Metabolism G Gamma-aminobutyric Acid Receptor Life Cycle GATA3 participate in activating the Th2 cytokine genes expression Generation of amyloid b-peptide by PS1 Glycolysis Pathway G-Protein Signaling Through Tubby Proteins Growth Hormone Signaling Pathway g-Secretase mediated ErbB4 Signaling Pathway H Hemoglobin's Chaperone HIV Induced T Cell Apoptosis HIV-1 defeats host-mediated resistance by CEM15 HIV-I Nef: negative effector of Fas and TNF Hop Pathway in Cardiac Development How does salmonella hijack a cell Human Cytomegalovirus and Map Kinase Pathways Hypoxia and p53 in the Cardiovascular system Hypoxia-Inducible Factor in the Cardiovascular System I IFN alpha signaling pathway IFN gamma signaling pathway IGF-1 Signaling Pathway IL 17 Signaling Pathway IL 18 Signaling Pathway IL 2 signaling pathway IL 3 signaling pathway IL 4 signaling pathway IL 5 Signaling Pathway IL 6 signaling pathway IL-10 Anti-inflammatory Signaling Pathway IL12 and Stat4 Dependent Signaling Pathway in Th1 Development IL-2 Receptor Beta Chain in T cell Activation IL22 Soluble Receptor Signaling Pathway IL-7 Signal Transduction Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages Induction of apoptosis through DR3 and DR4/5 Death Receptors Influence of Ras and Rho proteins on G1 to S Transition Inhibition of Cellular Proliferation by Gleevec Inhibition of Huntington's disease neurodegeneration by histone deacetylase inhibitors Inhibition of Matrix Metalloproteinases Insulin Signaling Pathway Integrin Signaling Pathway Intrinsic Prothrombin Activation Pathway Ion Channel and Phorbal Esters Signaling Pathway K Keratinocyte Differentiation L Lactose Synthesis Lck and Fyn tyrosine kinases in initiation of TCR Activation Lectin Induced Complement Pathway Leloir pathway of galactose metabolism Links between Pyk2 and Map Kinases Low-density lipoprotein (LDL) pathway during atherogenesis M Malate-aspartate shuttle Map Kinase Inactivation of SMRT Corepressor MAPKinase Signaling Pathway mCalpain and friends in Cell motility Mechanism of Acetaminophen Activity and Toxicity Mechanism of Gene Regulation by Peroxisome Proliferators via PPARa(alpha) METS affect on Macrophage Differentiation Mitochondrial Carnitine Palmitoyltransferase (CPT) System Monocyte and its Surface Molecules Msp/Ron Receptor Signaling Pathway mTOR Signaling Pathway Multi-Drug Resistance Factors Multiple antiapoptotic pathways from IGF-1R signaling lead to BAD phosphorylation Multi-step Regulation of Transcription by Pitx2 N Nerve growth factor pathway (NGF) Neuropeptides VIP and PACAP inhibit the apoptosis of activated T cells Neuroregulin receptor degredation protein-1 Controls ErbB3 receptor recycling Neutrophil and Its Surface Molecules NFAT and Hypertrophy of the heart (Transcription in the broken heart) NFkB activation by Nontypeable Hemophilus influenzae NF-kB Signaling Pathway Nitrogen-depedent regulation of Rtg1 and Rtg3 in TOR pathway NO2-dependent IL 12 Pathway in NK cells Nuclear receptors coordinate the activities of chromatin remodeling complexes and coactivators to facilitate initiation of transcription in carcinoma cells O Omega Oxidation Opposing roles of AIF in Apoptosis and Cell Survival Overview of telomerase protein component gene hTert Transcriptional Regulation Overview of telomerase RNA component gene hTerc Transcriptional Regulation OX40 Signaling Pathway Oxidation of odd-numbered chain fatty acid, from Propionyl-CoA to Succinyl-CoA Oxidation of Polyunsaturated Fatty Acid Oxidative reactions of the pentose phosphate pathway Oxidative Stress Induced Gene Expression Via Nrf2 P p38 MAPK Signaling Pathway p53 Signaling Pathway PDGF Signaling Pathway Pelp1 Modulation of Estrogen Receptor Activity Pertussis toxin-insensitive CCR5 Signaling in Macrophage Phosphatidylcholine Biosynthesis Pathway Phosphoinositides and their downstream targets. Phospholipase C d1 in phospholipid associated cell signaling Phospholipase C Signaling Pathway Phospholipase C-epsilon pathway Phospholipid Biosynthesis in E. Coli Pathway Phospholipids as signalling intermediaries Phosphorylation of MEK1 by cdk5/p35 down regulates the MAP kinase pathway PKC-catalyzed phosphorylation of inhibitory phosphoprotein of myosin phosphatase Presenilin action in Notch and Wnt signaling Proepithelin Conversion to Epithelin and Wound Repair Control Proteasome Complex Protein Kinase A at the Centrosome Proteolysis and Signaling Pathway of Notch PTEN dependent cell cycle arrest and apoptosis R Rab GTPases Mark Targets In The Endocytotic Machinery Rac 1 cell motility signaling pathway Ras Signaling Pathway Ras-Independent pathway in NK cell-mediated cytotoxicity RB Tumor Suppressor/Checkpoint Signaling in response to DNA damage Reelin Signaling Pathway Regulation And Function Of ChREBP in Liver Regulation of BAD phosphorylation Regulation of cell cycle progression by Plk3 Regulation of ck1/cdk5 by type 1 glutamate receptors Regulation of eIF2 Regulation of eIF4e and p70 S6 Kinase Regulation of hematopoiesis by cytokines Regulation of p27 Phosphorylation during Cell Cycle Progression Regulation of PGC-1a Regulation of Spermatogenesis by CREM Regulation of transcriptional activity by PML Repression of Pain Sensation by the Transcriptional Regulator DREAM Reversal of Insulin Resistance by Leptin Rgt1 in Yeast Glucose Induction Pathway Rho cell motility signaling pathway Rho-Selective Guanine Exchange Factor AKAP13 Mediates Stress Fiber Formation Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility Role of EGF Receptor Transactivation by GPCRs in Cardiac Hypertrophy Role of Erk5 in Neuronal Survival Role of MEF2D in T-cell Apoptosis Role of Mitochondria in Apoptotic Signaling Role of nicotinic acetylcholine receptors in the regulation of apoptosis Role of Parkin in the Ubiquitin-Proteasomal Pathway Role of PI3K subunit p85 in regulation of Actin Organization and Cell Migration Role of PPAR-gamma Coactivators in Obesity and Thermogenesis Role of Tob in T-cell activation S Selective expression of chemokine receptors during T-cell polarization Shuttle for transfer of acetyl groups from mitochondria to the cytosol Signal Dependent Regulation of Myogenesis by Corepressor MITR Signal transduction through IL1R Signaling of Hepatocyte Growth Factor Receptor Signaling Pathway from G-Protein Families