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Pathways IFN alpha signaling pathway
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Submitted by:  Walter ODell, PhDEmail Walter ODell, PhD Guru: Email

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Description: Description: Interferon alpha plays a role in viral infections. Signaling takes place through an IFN Recpetor complex consisting of two alpha chains (Type I receptor) complexed with Jak1 and Tyk2. These kinases phosphorylate Stat1 and Stat2 respectively.
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